Adipocytes have successfully been used to repair damage
to the heart muscle caused by severe heart attack. There
is also preliminary data to indicate they can be used to
treat cardiovascular disease, spine and orthopedic
conditions, congestive heart failure, Crohnís disease,
and to be used in plastic surgery.
Chondrocytes and Osteoblasts :
Chondrocytes and Osteoblasts have successfully been used
to grow bone and cartilage suitable for transplant. They
have also been used to grow intact teeth in animals.
Mesenchymal stem cells have successfully been used to
repair spinal cord injury and to restore feeling and
movement in paralyzed human patients. Since they can
form neuronal clusters, mesenchymal stem cells also have
the potential to treat neuronal degenerative disorders
such as Alzheimerís and Parkinsonís diseases, cerebral
palsy, as well as a host of other disorders.
Mesenchymal stem cells have more therapeutic
potential than any other type of adult stem cells.
MSCís are nonhematopoetic stromal cells that are capable of differentiating into and contributing to the regeneration of mesenchymal tissues.
They were first identified in bone marrow. They are a rare cell type and in BM they make up about 1 in 10,000 nucleated cells.
They are not immortal however they are capable of many population doublings in culture without loss of functionality.
When delivered systemically they migrate to sites of injury in animals. This property is called ďhomingĒ.
MSCís are regarded as nonimmunogenic. They also show the ability to suppress T cell activation.
Concise Review: Mesenchymal Stem Cells: Their Phenotype, Differentiation Capacity, Immunological Features, and Potential for Homing.
Stem Cells 2007;25:2739-2749
Tooth Cell banking is a proactive decision parents all over the world are now making.
With years of potential health benefits in return for simply saving your children's teeth, it's easy to see why.
Our three step process is simple, effective and non-invasive:
Step 1: Tooth Collection
You place the tooth in the collection box we provide. (CAREFULLY FOLLOWING ALL INSTRUCTIONS!)
When your childís tooth falls out all you have to do is put it in to fresh milk in the storage container along with frozen gel packs.
Pop it in the collection box and save it securely shut. The kit is then ready for delivery to our lab.
Step 2: Stem Cell Isolation
When we receive the tooth all the cells are isolated. We confirm the current health and viability of these cells.
Step 3: Tooth Cell Storage
We cryopreserve the tooth cells for your future use.
The sample is then divided into four cryo - tubes and each part is stored in a seperate location in our cryo-genic system.
This means that even in the unlikely event of a problem with one of our storage units, there will be another sample available for use.
The cells are preserved in liquid nitrogen vapour at a temperature of less than -150c. This preserves the cells and maintains their potential potency.
Not all teeth hold the same tremendous potential. The teeth shown in red on the diagram here have been published to contain these unique types of cells.
As indicated, the primary molars require special attention and processing. Please contact us to discuss whether storing the cells from one of these teeth is appropriate for your situation.
The first 48 hours after the tooth is out of the mouth are critical. The tooth must be prepared, packaged and shipped and received at laboratory during this time to maximize a successful isolation.
The most important contribution you can make to the success of this process is to be prepared in advance for the next time your child's tooth or your wisdom tooth becomes loose.