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Bio-Oss l Bio-Gide

Bonegraft : Geistlich Bio-Oss®

 

Biofunctionality

Because of the close resemblance to the human bone Geistlich Bio-Oss® is incorporated into the natural modelling and remodelling process. The highly porous structure of Geistlich Bio-Oss® offers plenty of space for blood vessels to form (angiogenesis) and new bone to be deposited (osteogenesis). The microstructure of the Geistlich Bio-Oss® surface supports optimal ingrowth of osteoblasts, which are responsible for bone formation. Thus the Geistlich Bio-Oss® particles do become an integral part of the newly forming bone framework. The slow rate of conversion of Geistlich Bio-Oss® to autogenous bone (remodelling) stabilises the framework and enables the volume of the augmentate to be maintained on a long term perspective. These biofunctional processes make Geistlich Bio-Oss® unique.

Bio-Oss bondgraft

High porosity – like human bone Enhances blood vessel formation and bone cell migration through the coarse meshed, interconnecting pore system.
Large internal surface area – like natural bone Allows intimate contact with new bone tissue.
Fine crystalline structure – like natural bone Allows integration into the natural bone remodelling process.
Chemical composition – like natural bone Results in high tissue compatibility.

Macroporous mineral structure of Geistlich Bio-Oss
Macroporous mineral structure of Geistlich Bio-Oss® (SEM 50x)
Macroporous mineral structure of human bone
Macroporous mineral structure of human bone (SEM 50x) - high similarity to Geistlich Bio-Oss®.

The All-rounder

Implantological indications: To meet functional and esthetic demands when placing implants, regeneration procedures are necessary in approximately 40% of all cases. The use of Geistlich Bio-Oss® and Geistlich Bio-Gide® as part of Guided Bone Regeneration (GBR) is nowadays regarded as the standard therapy to buiding up bone and soft tissue in the following indications:

• Peri-implant defects
• Extraction sockets
• Sinus floor elevations
• Horizontal augmentations
• Vertical augmentations

Periodontal indications: In order to preserve the tooth in the long-term, regenerative periodontal therapy aims to restore the complete periodontium consisting of cementum, ligament and bone. This requires a matrix, which supports the regeneration of these tissues, and a membrane, which prevents the long marginal epithelium from ingrowth. Numerous studies, some including human histologies, show the high regeneration potential of Geistlich Bio-Gide® and Geistlich Bio-Oss® in periodontal indications.

Cranial and Maxillofacial indications: As an innovative company Geistlich constantly strives in collaboration with the leading surgeons, to disvover new treatment methods and indications for regenerative products. Our biomaterials are being used increasingly for cranial and maxillofacial indications.

Long-term success

True success is rarely achieved overnight – it only becomes apparent after a certain period. Geistlich Bio-Oss® took its time confirming its effectiveness clinically, since only the well-tried and tested products instil real confidence- confidence that is reflected in 24 years experience and in more than 650 publications, many of which document the long-term success of treatment with Geistlich Bio-Oss®. Thanks to its biofunctionality, Geistlich Bio-Oss® has delivered promising results also as a carrier matrix for growth factors.


Macroporous mineral structure of Geistlich Bio-Oss

Transmission eiectron micrograph of the Geistlich Bio-Oss® - bone interface after 7 years. There is close contact between the particle and the bone, which presents feature bone.

Macroporous mineral structure of human bone

9 years postoperatively : new bone is in direct contact with the Geistlich Bio-Oss® particles. Bone is forming bridges between bone trabeculae and Geistlich Bio-Oss® as well as between the particles of the inorganic bone matrix.

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